Please check the calendar for more info.

Date	Speaker	Title	Poster
Oct 25th	Ya Ha	Crystal Structure of a Rhomboid Family Intramembrane Protease	:
Nov 27th	Carola Hunte	Sodium and Proton Transport: Structural Basis and Beyond	:
Dec 19th	Karin Reinisch	Two tales–of quality control for non-coding RNAs and the assembly/architecture of a membrane tethering complex	:
Feb 1st	Chris Garcia	New structural insights into neurotrophin and cytokine receptor recognition and activation	:

CMCD Learning

Academics

Molecular Case Studies Courses (IDB):

Graduate Credit or IDB Certificate (for post-docs, affiliates and faculty)

E-mail Meg Bentley to enroll.

Molecular Visualization - A Case Study of Clathrin Coats. P. Sliz, J. Chou, S. C. Harrison; Sept 18 - 25 2006.

:class1 :class2

3DX Data Processing - A Case Study of Notch Transcriptional Complex. Piotr Sliz, Yunsun Nam and Spyros Artavanis-Tsakonas; Nov 28 - Dec 5th 2006. (Class is full)
3DX Phasing. P. Sliz, R. Gaudet, T. Rapoport, Dan Kahne; Feb 14, 21 2007. Enroll early - class size is limited

Biophysics Courses:

Biophysics 204: Structural Biology From Molecules to Cells. S. C. Harrison. Spring 2007

BCMP Courses:

BCMP 228: Macromolecular NMR. G. Wagner, J. Chou, V. deSouza, J. Sun, S. Hyberts, G. Heffron; Fall 2006.

Non-credit Courses

The following course will be offered thorugh SBGrid:

Nov 21 2006, UNIX for structural biologists.

Journal Club

Weekly Journal Review Club meeting organized by CMCD member laboratories. Tuesday, noon, bring-your-own lunch.

Location: HMS, BldgC, Rm 216

For more information please contact jrc@crystal.harvard.edu

Fall 2006
Date	Theme	Editor 1	PDF	Editor 2	PDF
Sep 19th	Complexes	Jawdat	:	Kelly	—-
Sep 26th	Membrane P	Yunsun	:	Stefan	:
Oct 3rd	Viral P.	Corinne	:	Mihnea	:
Oct 10th	Methods	X-ray: Piotr	:	NMR:Jason	:
Oct 17th	Complexes	Kelly	:	Jawdat	:
Oct 24th	Membrane Prot.	Stefan	:	Yunsun	—-
Oct 31st	Viral Prot.	Corrine		Mihnea	:
Nov 7th	Methods	EM: Mattias	—	2DX: Rich	:
Nov 14th	Complexes	Kelly	:	Jawdat	—
Nov 21st	Membrane Prot.	Stefan	:	Yunsun	:
Nov 28th	Viral Prot.	Corrine	:	Mihnea	:
Dec 5th	Methods	3DX: Piotr	:	NMR: Jason&Matt	:
Dec 12th	Methods	EM: Mattias	:	SP: Daniel	:

Paper of Fall 2006: TBD

Spring 2007
Date	Theme	Editor 1	PDF	Editor 2	PDF
Jan 9th	Complexes	Kelly		Jawdat	:
Jan 16th	Membrane Prot.	Stefan		Yunsun
Jan 23rd	Viral Prot.	Corrine		Mihnea
Jan 30th	Methods	3DX: Piotr

Research Infrastructure

The Structural Biology Grid computing group, (SBGrid) provides comprehensive consulting and computing services to all CMCD members and offers software support to more then fifty laboratories across the country. For more information please visit the SBGrid website: www.SBGrid.org or contact Piotr Sliz directly.

SBGrid Newsletter:

Electron Microscopy

Molecular Electron Microscopy HMS Core Facility

NMR

NMR Spectrometer Hardware List - Wagner Lab
Francis Bitter Magnet Laboratory - MIT
The 500 MHz spectrometer with Varian Unity Inova console is equipped with three radio frequency channels, pulse field gradients and a room temperature 5mm HCN probe. Division of Hemostasis and Thrombosis, BIDMC. $5/hr; contact Natalia Beglova.

X-ray Crystallography

Synchrotron Radiation

The dates for our sixth data collection synchrotron run at APS are now available. Data collection time is allocated by the CMCD Synchrotron Committee. Slots at both SBC and NE-CAT are available. Please e-mail Piotr Sliz to request time (id@crystal.harvard.edu).

You must be a registered APS user to apply.

Fall 2006

CMCD@APS17 ID24, Oct 25-26 (Harrison, Chen)
CMCD@APS18 ID24, Oct 27-28 (Labs: Cantley, Hogle, Walker)
CMCD@APS19 ID19, Oct 27-28 Cancelled
CMCD@APS20 ID19, Dec 8-9 (Rapoport)
CMCD@APS21 ID24, Dec 13-14 (Walker,Verdine)
CMCD@APS22 ID24, Dec 15 - (Harrison)

Spring 2007

CMCD@APS23 ID24, Feb 9-11 (2/9-10: Hogle, 2/11: Harrison)
CMCD@APS24 ID24, March 9-10 (3/9: SCH)
CMCD@APS25 ID24, Apr 8-9

In-house Sources

Location	PI	Generator	Mirrors	Detector	Cryo	Ratings
DFCI	MJE	Rigaku	Osmic Blue	Mar300	Siemens LT2	1
DFCI	MJE	Rigaku	JDG Focus	Mar300	Siemens LT2	1
DFCI	MJE	Rigaku	Xenox	Mar345	Siemens LT2	3
SGM	SCH	Microstar	Montel	2xMar345	Oxford	8
BLGC	JH	Eliot	JDG Focus	Mar345	Siemens	4
BLDC	JH	Bruker	JDG Focus	Mar345	Siemens	1